Adiponectin-cre是什么
WebAdipoq-Cre BAC transgenic mice are a Cre-lox tool for deletion of floxed sequences in white adipose tissue and brown adipose tissue, but not in activated or resident macrophages. … WebNov 15, 2024 · The authors found that Adiponectin-cre marked almost the entire population of Lepr-cre-marked BMSCs, but not periosteal cells. Of note, BMSCs marked by Adiponectin-cre/creER have been previously reported as marrow adipogenic lineage precursors (MALPs). 8 In contrast, Gli1-creER marked 20% of periosteal cells both in …
Adiponectin-cre是什么
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Web该Cre小鼠与FloxP小鼠交配后,在Cre特异表达的组织或者器官或细胞中,两个FloxP位点间的外显子或元件将被删除,达到条件性敲除或过表达的目的。 Cre-loxP重组系统是一种位点特异的基因重组技术,被广泛应用于特异位点的基因敲除、基因插入、基因翻转和基因 ... WebMay 5, 2016 · Adiponectin is renoprotective in multiple mouse models and clinical studies suggest that adiponectin is beneficial to kidney disease outcomes (Sweiss and Sharma, …
WebAdiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels as well as fatty acid … WebSep 29, 2024 · Discover how adiponectin levels and adiponectin function influence body weight and health, and whether you need adiponectin testing. Adiponectin is a molecule secreted mainly by the body’s fat cells ( adipocytes) that is linked to weight loss and weight gain. In this article, discover adiponectin hormone functions, the adiponectin-obesity ...
WebJun 24, 2024 · Cre- littermates serve as control. In keeping with the unique expression of adiponectin Cre in adipocytes and their precursors all Cre+ products of the mating contain no discernable WAT confirmed by virtually undetectable circulating adiponectin or leptin as well as visfatin and, resistin . BAT is also absent and as a result, FF mice are cold ... WebApr 4, 2024 · To determine the metabolic effects of direct FGF21 signaling to adipose tissue, we generated mice lacking the obligate FGF21 coreceptor, β-klotho (gene symbol: Klb), specifically in adipose tissue (KLB AdipoKO mice) by crossing KLB fl/fl mice with Adiponectin-Cre transgenic mice. As expected, β-klotho mRNA (Figure 1A ) and protein …
WebMA1-054 detects adiponectin from human, rabbit and mouse samples. MA1-054 has been used successfully in Western blot, immunofluorescence, and ELISA procedures. By Western blot this antibody detects ~30 kDa protein representing Adiponectin in 3T3-L1 adipocytes. Immunofluorescence and ELISA of Adiponectin can also be performed using MA1-054.
WebThe adiponectin gene is located on chromosome 3q27. This gene encodes a 244-amino acid protein composed of an amino-terminal signal peptide, a collagen-like domain at the N-terminus, and a globular domain at the C-terminus (Fig. 1).The globular domain is homologous to proteins such as collagens VIII and X and complement factor C1q 25 and … chowdhary surnamechowdhary pronunciationWebThe Jackson Laboratory adiponectin cre adipoq cre transgenic mice Adiponectin Cre Adipoq Cre Transgenic Mice, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more genial online mathe trainerWebJun 1, 2010 · Adiponectin (also described as Adipo Q, Acrp30, apM1), a 30-kDa adipokine, was discovered in both human and rodent adipose tissue as well as in the cultured … chowdhary \u0026 coWebFeb 14, 2013 · To circumvent the possible side effects of gene deletion of the aP2-Cre in tissues other than adipocytes, two laboratories have developed adiponectin-Cre transgenic mice (Adipoq-Cre), with expression of a Cre recombinase driven by the promoter/regulatory regions of the mouse adiponectin locus using a bacterial artificial chromosome (BAC ... chowdhrey naseer a mdWeb胶原蛋白/ Collagen 背景. 胶原蛋白(Collagen)是人体中最丰富的蛋白质,约占蛋白质组成的三分之一,具有至少16种不同的亚型。. 胶原蛋白几乎在所有组织中都可以检测到。. 胶原蛋白在肌腱,韧带和皮肤等结缔组织中作为结构蛋白起着至关重要的作用。. 它提供 ... chowdhry bashir a mdWeb图1. TdTomato的打靶策略[1] 这种鼠在正常情况下由于3×stop的存在并不能表达红色荧光,当与Cre鼠或TAM激活的CreERT2鼠交配后,产生的后代由于Cre重组酶切割loxp位点之间 … genial o south park