Chlorotrityl chloride resin
WebOSHA Vacated PELs: 2-Chlorotrityl Chloride Resin: No OSHA Vacated PELs are listed for this chemical. Divinyl benzene: 10 ppm TWA; 50 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or … WebApr 13, 2024 · Volza can help you reduce your cost of procurement of Chlorotrityl chloride resin & improve your supply chain as it allows you to choose from the list of most economical, active and reliable suppliers of Chlorotrityl chloride resin in ...
Chlorotrityl chloride resin
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Web2-Chlorotrityl chloride resin can be cleaved under extremely mild acid conditions that leave Boc/tBu based protecting groups in place. … WebJul 15, 1999 · Dried 2-chlorotrityl chloride resin (100 mg) was swelled for 30 min in DMF (10 ml) and an excess of 0.01 N NaOH (30 ml) was added dropwise slowly by stirring. The mixture was stirred for another 30 min and the pH-value of the mixture controlled, if pH>10 the stirring was continued for another 30 min, if pH<10, the mixture was diluted with …
WebLoading the Resin To a 100mL peptide synthesis vessel, add 2-chlorotrityl chloride (CTC) resin (1.1 mmol/g, 0.360 g, 0.400 mmol). Add 20 mL DMF and allow them to swell for 30 min under N 2. Drain the beads under vacuum and add 10 mL DMF. Add 500 mg Fmoc-Ala-OH (1.60 mmol) and 2.5 mL i- Pr 2 EtN, and mix under N 2 for 15 min. Web2-Chlorotrity chloride resin is slightly less acid-labile than Trityl Resin and thus more widely used in solid phase peptide synthesis [1-6]. This resin has been also widely used …
WebFirst, we loaded 2-chlorotrityl chloride resin for carboxylated peptides. The first amino acid was loaded manually by treating 1 g of 2-chlorotrityl chloride resin (1.6 mmol/g of Cl) swollen in DCM with a solution of 0.6 mmol amino acid and 1 mL of iPr 2 Net in 5 mL of DCM for 1 h, followed by adding 5 mL of MeOH and agitating for an additional ... WebApr 4, 2024 · 2-chlorotrityl chloride resin laboratory research chemical not restricted-prohibited : united states: india: 100: 29420090: 2-chlorotrityl chloride resin 100-200 mesh br-1060 : greece: india: 15000: 39039090: resin >> chloride resin 2ctc resin cas-no 42074-68-0 2-chlorotrityl chloride resin: germany: india: 2: 60 more
WebThe polystyrene-based 2-chlorotrityl resin was originally used in the synthesis of peptides using an Fmoc-amino acid/carboxyl-linked protocol. While traditionally employed to prepare a number of biologically active peptides, the resin has received increasing attention as a support for the synthesis …
WebDec 27, 2024 · 2-Chlorotrityl Chloride and 4-Methylbenzhydryl Bromide Resin Loading Using the Mixture of Organic Solvents: A “Greener” Alternative to Dichloromethane and … refworks microsoft wordWebMay 6, 2014 · Synthesis of Fmoc hydrazine 2CTC resin 2-Chlorotrityl chloride resin (loading=0.57 mmol/g) (2 g) was swollen in CH 2 Cl 2 (16 mL) at 0 °C. Fmoc hydrazine hydrochloride (1.16 g, 4 equiv) and diisopropylethylamine (2.02 mL, 10 equiv) were dissolved in DMF (20 mL) and CH 2 Cl 2 (4 mL). refworks northeasternWeb2-Chlorotrityl chloride C19H14Cl2 CID 94524 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … refworks ntuWebFollowing the successful introduction of two benign solvents for cleaving protected acid peptide fragments from 2-chlorotrityl chloride (2-CTC) resin, there is a need to green the cleavage process for obtaining … refworks nhs scotlandWeb2-Chlorotrityl chloride resin (100-200 mesh), 1% DVB 855017 Sigma-Aldrich 2-Chlorotrityl chloride resin (100-200 mesh), 1% DVB Download Zoom Novabiochem® … refworks new versionWebGeneral description. An acid-labile resin for the solid phase immobilization of alcohols [1-5], amines [4, 6-12], sugars [13], O- and N-linked hydroxylamines [14, 15], imidazoles [16] and carboxylic acids [16]. Release of these functionalities is generally achieved using 1-5% TFA in DCM containing 5% TIS. Amines can also be cleaved with 30% ... refworks nottingham trentWebJul 1, 1991 · Abstract. The esterification of 2-chlorotrityl chloride resin with Fmoc-amino acids in the presence of DIEA is studied under various conditions. High esterification yields are obtained using 0.6 ... refworks overleaf