Cub domain-containing protein

WebSummary. This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. WebNational Center for Biotechnology Information

CUB-domain-containing protein 1 overexpression in solid …

WebAbstact. To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological … WebMar 23, 2024 · The structure of CUB domains consists of a beta-sandwich with a jelly-roll fold. Almost all CUB domains contain four conserved cysteines that probably form two … simple ez hosting https://ccfiresprinkler.net

CUB-domain–containing protein 1 (CDCP1) activates Src to …

WebLaw, M. E., Ferreira, R. B., Davis, B. J., Higgins, P. J., Kim, J.-S., Castellano, R. K., … Law, B. K. (2016). CUB domain-containing protein 1 and the epidermal ... WebDec 3, 2012 · Specific cleavage of the transmembrane molecule, CUB domain-containing protein-1 (CDCP1), by plasmin-like serine proteases induces outside–in signal transduction that facilitates early stages of ... WebJun 14, 2010 · CUB domain–containing protein 1 (CDCP1) is a membrane protein that is highly expressed in several solid cancers. We reported previously that CDCP1 regulates … rawhide pressed bones

CDCP1 CUB domain containing protein 1 [ Homo sapiens …

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Cub domain-containing protein

Structural Requirements for Cub Domain Containing …

WebJul 15, 2024 · CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease Clinical … WebThe appearance of synapses was a crucial step in the creation of the variety of nervous systems that are found in the animal kingdom. With increased complexity of the organisms came a greater number of synaptic proteins. In this review we describe synaptic proteins that contain the structural domains CUB, CCP, or TSP-1. These domains are found in …

Cub domain-containing protein

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WebCUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix degradation during tumor invasion and metastasis in a tyrosine phosphorylation-dependent manner. WebNing Zhao's 14 research works with 118 citations and 1,017 reads, including: Theranostic Targeting of CUB Domain–Containing Protein 1 (CDCP1) in Multiple Subtypes of Bladder Cancer

WebMay 5, 2024 · We here demonstrate that the CUB-like-domain containing protein RBT-1 acts as a functional receptor of Cry6A, which mediates the intestinal cell interaction and … WebDec 7, 2004 · PTHR24251:SF37 CUB DOMAIN-CONTAINING PROTEIN 2 1 hit; PTHR24251 OVOCHYMASE-RELATED 1 hit; PROSITE. View protein in PROSITE; PS01180 CUB 3 hits; Pfam. View protein in Pfam; PF00431 CUB 3 hits; SMART. View protein in SMART; SM00042 CUB 3 hits; SUPFAM. SSF49854 Spermadhesin, CUB …

WebDec 9, 2010 · Using such approaches, we identified CUB-domain–containing protein 1 (CDCP1) as a membrane protein that is up-regulated in highly metastatic melanomas. … WebJun 1, 2008 · One such antigen, CUB domain-containing protein 1 (CDCP1), was recognized by monoclonal antibody 25A11 and is a single transmembrane molecule highly expressed in several metastatic cancers as well ...

WebOct 3, 2024 · Abstract. Rationale: An antibody-drug conjugate (ADC) is a targeted therapy consisting of a cytotoxic payload that is linked to an antibody which targets a protein …

WebAug 1, 2009 · The function of CUB domain-containing protein 1 (CDCP1), a recently described transmembrane protein expressed on the surface of hematopoietic stem cells and normal and malignant cells of different tissue origin, is not well defined. The contribution of CDCP1 to tumor metastasis was analyzed by using HeLa carcinoma cells … rawhide power plant wellington coWebOct 2, 2024 · Comment: annotation includes both PSPI/PSPII interaction residues highlighted. Download Cn3D for Viewing 3D Structure Scroll to Sequence Alignment … simple eye shadow blending tutorialsWebDec 31, 2012 · Cub domain containing protein 1 (CDCP1) is strongly expressed in tumors derived from lung, colon, ovary, or kidney. It is a membrane protein that is phosphorylated and then bound by Src family … rawhide power stationWebAbstact. To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological conditions and healthy women and in a number of other cancer … simple eye vs compound eyeWebOct 31, 2006 · PTHR24046:SF4 SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1 1 hit; PROSITE. View protein in PROSITE; PS00010 ASX_HYDROXYL 6 hits; PS01180 CUB 1 hit; PS01186 EGF_2 6 hits; PS50026 EGF_3 6 hits; PS01187 EGF_CA 6 hits; Pfam. View protein in Pfam; PF12662 cEGF 1 hit; … simple eyeshadow with blue eyelinerWebMar 28, 2011 · Signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) is a secreted glycoprotein that is overexpressed in lung cancer tumor tissues and is correlated with the invasive ability in a lung ... simple eyes makeup picsWebFeb 15, 2024 · CUB domain containing protein 1 (CDCP1), also known as Trask, gp140, SIMA135, and CD318, is a type I single-pass membrane protein that is highly overexpressed in a variety of solid tumors (12 – 14). simple eyeshadows