Early endosome antigen 1

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August undefined, 2024

Web3 hours ago · Our studies found that CRB3 could colocalize with EEA1-positive early endosomes, CD63-positive late endosomes and Rab11-positive recycling endosomes . In addition, after 2 hours of ... sequentially. Then, antigen retrieval was performed in Tris-EDTA buffer (pH 9.0) heated to 95°C for 20 min. Endogenous peroxidase activity was … WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in …

Anti-EEA1 Antibody - Sigma-Aldrich

WebNov 28, 2024 · c Statins counter Mycobacterium tuberculosis-induced phagosome arrest by inducing the expression of early endosome antigen 1 (EEA1), which might be due to increased Ca 2+ levels in macrophages. WebEarly endosomes are a major cytoplasmic sorting compartment from which receptors and ligands may be distributed to various sites within the cell. Early endosome antigen 1 (EEA1) is a 180 kDa hydrophilic peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence studies show that EEA1 colocalizes to early … cupid ukraine

EEA1 early endosome antigen 1 [ Homo sapiens (human) ]

WebJan 3, 2024 · EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast … WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in segments centered around amino acids 515 and 645. EEA1 contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for N … WebFeb 1, 2004 · Rab5 together with early endosome antigen 1 (EEA1) 118,119,120 — a phosphoinositide-binding protein — regulate fusion between primary endocytic vesicles and sorting endosomes. More … dj zoo 105

Anti-EEA1 antibody, Mouse monoclonal - Sigma-Aldrich

Essential role of Ca2+/calmodulin in Early Endosome …

WebEEA1, early endosome antigen 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog EEA1, early endosome antigen 1. Synonyms MST105, MSTP105, ZFYVE2 Links HGNC:3185. NCBI Gene ID: 8411. neXtProt AC: NX_Q15075. UniProt: Q15075. Chr Location ... WebEssential role of Ca2+/calmodulin in Early Endosome Antigen-1 localization. Ca2+ is an essential requirement in membrane fusion, acting through binding proteins such as … cupid projectWebJan 30, 2012 · Depletion of Rabenosyn-5, but not of other early endosomal proteins such as early endosome antigen 1, resulted in impaired transferrin uptake and lysosomal degradation of transferrin receptors. These studies reveal a critical role for Rabenosyn-5 in determining the fate of transferrin receptors internalized by clathrin-mediated endocytosis … dj zoom

"WebRab22a is an important small GTPase protein the molecule that is involved in intracellular transportation and regulation of proteins. It also plays an important role in antigens uptake, transportation, regulation of endosome morphology, and also regulates the transport of antigens to MHC (Major Histocompatibility Complex) molecules. To investigate the role … " - Early endosome antigen 1

Early endosome antigen 1

Endocytic recycling Nature Reviews Molecular Cell …

WebJul 9, 2024 · The derived amino acid sequence was found to be 99% identical to a 180 kd peripheral endosomal protein named early endosome antigen (EEA1). Results: … WebMar 3, 2015 · To investigate whether GALNT1 regulates EGFR trafficking, immunofluorescence staining of GALNT1 knockdown HA22T and PLC5 cells treated with EGF 10 ng/ml was performed to analyze for co-localization of EGFR (red) with early endosome antigen 1 (EEA1) (green) or lysosomal associated membrane protein 1 …

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WebJun 2, 1995 · Early endosomes are cellular compartments receiving endocytosed material and sorting them for vesicular transport to late endosomes and lysosomes or for … WebApr 27, 2024 · Therefore, we, co-transfected cells with the well-known tethering protein early endosome antigen 1 (EEA1) tagged to GFP (EEA1-GFP) (Bergeland et al., 2008; …

WebSep 16, 2016 · Popular answers (1) The original characterization of "Early Endosomes" is defined by those compartments labeled by transferrin after 20 to 30 minutes of addition. EEA1 (early endosome antigen 1 ... WebMay 15, 2015 · Following entry into host cells, OMVs migrate to early endosome antigen 1 (EEA1)-labelled endosomes where they interact with and are detected by nucleotide-binding oligomerization domain ...

WebItem Monkey Early Endosome Antigen 1 ELISA Kit; Company MyBioSource.com; Price Pricing Info Supplier Page View Company Product Page; Catalog Number MBS051694; Quantity 96 Strip Wells; Applications ELISA; Reactivity Monkey; Detection Target Early Endosome Antigen 1 WebJul 10, 2024 · At this stage, ingested materials can be recycled back to the plasma membrane, sent to the trans-Golgi Network (TGN), or degraded through endosomal acidification. Each compartment in the pathway is marked by characteristic proteins, such as early endosome antigen 1 (EEA1), lysosomal-associated membrane protein 1 …

WebEarly endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations. Zinc-finger-like ...

WebThe gene Early Endosome Antigen 1 (EEA1) encodes for around 1400 amino acid proteins. It is a peripheral membrane protein associated with the cytoplasmic face of early endosomes. EEA1 is a autoantigen associated with subacute cutaneous systemic lupus erythematosus and is a coiled-coil protein localized to early endosomes and cytosol. cupid pads bra ukWebSep 2, 2005 · The FYVE domain is defined by the three conserved elements: the N-terminal WxxD, the central RR/KHHCR, and the C-terminal RVC motifs that form the PtdIns(3)P binding site seen in the solution and crystal structures of early endosome antigen 1 (EEA1), Hrs, and Vps27p FYVE (6, 13, 17, 18).The PtdIns(3)P headgroup is coordinated … cupid pads ukWebDec 14, 2024 · EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains … dj zukWebEarly endosome antigen 1 (EEA1) is an early endosomal protein that contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for … dj はWebSep 17, 2024 · The crucial effectors of Rab5 are early endosome antigen-1 (EEA1) [28, 29], rabaptin-5 [30, 31, 37], rabenosyn-5 [32, 38], APPL1/2 [33, 34], and ZFYVE21 (Table 1). EEA1, a key effector of Rab5 with a molecular weight of 162 kD, is a biomarker for early endosomes and has a parallel coiled-coil homodimer structure. cupid\\u0027s bowWebThank you for your interest in NeuroMab™ anti-Human Early Endosome Antigen 1 (EEA1) IgG fraction Antibody. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n): cupid\u0027s bow brenda jacksonThe gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate through its C-terminal FYVE domain and forms a homodimer … See more EEA1 is a RAB5A effector protein which binds via an N-terminal zinc finger domain and is required for fusion of early and late endosomes and for sorting at the early endosome level. See more Due to the proteins importance in vesicular trafficking, a number of intracellular bacteria prevent EEA1 recruitment to the vacuole. Mycobacterium tuberculosis is known to inhibit the … See more • early+endosome+antigen+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural … See more • endosome • Phosphatidylinositol 3-phosphate • FYVE domain See more dj zucaro